Antuc-L (Rabeprazole 20 mg + Levosulpiride 75 mg SR Capsules)

Overview:

ANTUC-L is a Rabeprazole and Levosulpiride combination. Rabeprazole inhibits gastric acid secretion and Levosulpiride is a prokinetic agent, used in the management of functional dyspepsia on the basis of dopaminergic pathways controlling gastrointestinal motility.

 


Rabeprazole belongs to the class of proton pump inhibitor (PPI). Levosulpiride, a substituted benzamide and a selective dopamine D2-receptor antagonist

ANTUC-L Capsules can be used in the treatment of following conditions:

  • Postoperative vomiting and vomiting during cancer chemotherapy.
  • Erosive or ulcerative GERD.
  • Dyspepsia.
  • Healing of duodenal ulcers.
  • Zollinger Ellison Syndrome.
  • Gastroparesis.


One ANTUC-L Capsule daily on an empty stomach, or as directed by Physician.

Rabeprazole suppresses gastric acid secretion by specific inhibition of the hydrogen-potassium adenosine triphosphatase (H+, K+-ATPase) enzyme system found at the secretory surface of parietal cells.

Levosulpiride is a sulpiride isomer that exerts its prokinetic action through a dual mechanism: 1) as a D(2) dopamine receptor antagonist and 2) as a serotonin 5HT(4) receptor agonist, conferring this drug with a cholinergic effect.. Levosulpiride is effective in delayed gastric emptying and may be related to its action on the gastric motor function.