Doxinis-CV (Cefpodoxime Proxetil 200 mg + Clavulanic Acid 125 mg Tablets)

Overview:
DOXINIS-CV Tablets contain Cefpodoxime Proxetil and Clavulanic Acid. It can be used as an empiric therapy and step-down to oral therapy (switch therapy). Stepping down from IV to oral therapy provides comfort to patients, avoids the hazards of parenteral delivery, early discharge from hospital and better compliance.
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Cefpodoxime is an oral third generation cephalosporin antibiotic. Clavulanic Acid is a semisynthetic beta-lactamase inhibitor isolated from Streptomyces.

DOXINIS-CV Tablets can be used in the treatment of the following conditions:

  • Acute bacterial exacerbations of chronic bronchitis
  • Acute community acquired pneumonia
  • Upper and lower respiratory tract infections
  • Skin and soft tissue infections
  • Urinary tract infections
  • Pharyngitis and/or tonsillitis
  • General gonorrhea and rectal gonococcal infections
  • Acute maxillary sinusitis


1-2 DOXINIS-CV Tablets every 12 hours for 7-14 days or as directed by Physician.

Cefpodoxime is active against a wide spectrum of Gram-positive and Gram-negative bacteria. It inhibits cell wall synthesis. The bactericidal activity of Cefpodoxime results from its inhibition of cell wall synthesis.
Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. It is an enzyme inhibitor that enhances the antibacterial activity.