Overview of Aceclofenac + Rabeprazole Capsules:

NISMOL PLUS Capsule contains Aceclofenac 200mg and Rabeprazole 20mg. Aceclofenac has an excellent efficacy against chronic joint diseases, including rheumatoid arthritis, osteoarthrosis and ankylosing spondylitis, as well as dentalgia, post-operation pain or post-delivery pain. This drug shows an excellent therapeutic effect in that it easily penetrates into inflammatory tissues occurring in a joint and the like, and thus exhibits an excellent action of inhibiting prostaglandin production, as compared to other anti-inflammatory analgesic drugs. Rabeprazole act as an anti-ulcerative drug.

 

 


Aceclofenac- NSAID, Analgesic, Antiinflammatory, Anti arthritic. Rabeprazole- Proton pump inhibitor

NISMOL PLUS Capsule can be used in the managment of pain and inflammation in the following conditions:

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Acute gout
  • Post operative pain
  • Dental pain
  • Painful musculoskeletal condition
  • Low back pain


One NISMOL PLUS Capsule daily.

Aceclofenac inhibits cyclooxygenase (COX) activity and to suppress the PGE2 production by inflammatory cells, by inhibiting IL-Beta & TNF in the inflammatory cells (Intracellular Action). Rabeprazole suppress gastric acid secretion by inhibiting gastric H+K+ATPase at the secretory surface, of the gastric parietal cells. Rabeprazole act by blocking the H+P+ ATPase enzyme of the gastric parietal cells, thus inhibit last stage of gastric acid secretion.