Nistreo (Aztreonam 1g Injection)

NISTREO Injection contains Aztreonam. Aztreonam exhibits potent and specific activity in vitro against a wide spectrum of gram-negative aerobic pathogens including Pseudomonas aeruginosa.


Aztreonam belongs to the class of monobactams beta- lactam antibiotic.

NISTREO Injection can be used in the treatment of the following conditions:

  • Septicemia.
  • Skin and soft tissue infection.
  • Urinary tract infection.
  • Intra abdominal infection.
  • Respiratory tract infection.
  • Adjuvant therapy to surgery caused by susceptible organisms.
  • Uncomplicated Gonorrhea.
  • Cystitis.
  • Gynecologic and obstetric infection.

1-2g NISTREO Injection every 6-8 hours by IM or IV, or as directed by Physician.

Aztreonam cause the inhibition of bacterial cell wall synthesis due to its high affinity for penicillin binding protein 3 (PBP3). By binding to PBP3, Aztreonam inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.