Overview of Nimesulide + Serratiopeptidase Tablets:
PEPTINIM-15 Tablet contains Nimesulide 100mg + Serratiopeptidase 15mg.
Nimesulide is a pain killer NSAIDs drug, characterized by a fast onset of activity for pain relief and also used for degenerative joint disease. Serratiopeptidase is a bacterial peptide-cleaving enzyme (proteolytic enzyme). It is also a potent anti-inflammatory agent that exerts fibrinolytic and anti-edematic property. It is a centrally acting agent for painful musculoskeletal conditions. Serratiopeptidase reduces swelling, pain, pus and haematomas. Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. It is used for the treatment of acute pain, the symptomatic treatment of osteoarthritis.

Serratiopeptidase is a proteolytic enzyme, powerful anti-inflammatory and an anti-edemic agent. Nimesulide belong to the class of NSAID of the sulphonanilide.

PEPTINIM-15 Tablets can be used in the treatment of the following conditions:

  • Acute inflammatory pain
  • Painful Osteoarthritis
  • Primary dysmenorrhoea
  • Post-partum haematomas
  • Breast engorgements
  • Pregnancy-related thrombophlebitis
  • Post-operative trauma
  • Painful inflamed dermatoses
  • Dental infections & inflammation
  • Sports injury etc.

Adults: One PEPTINIM-15 Tablet twice daily or as directed by Physician.

Serratiopeptidase is an anti-inflammatory proteolytic enzyme that binds to the alpha-2-macroglobulin in the blood, which helps to mask its antigenicity. Then it is slowly transferred to the site of inflammation. It inhibits PGE2 at the site of inflammation and neutrophils and thereby helps in pain relief. Nimesulide inhibits prostaglandin synthesis on the COX-2 enzyme.