ROSIVAC Tablets can be used in the treatment of the following conditions:

• Hyperlipidemia and mixed dyslipidemia
• Hypertriglyceridemia
• Hypercholesterolemia
• Primary Dysbetalipoproteinemia (Type III Hyperlipoproteinemia)
• Slowing the progression of Atherosclerosis
• Primary prevention of cardiovascular diseases

One ROSIVAC Tablet daily with/without food at any time of the day or as directed by Physician.

Rosuvastatin that is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor for cholesterol. The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering.

Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.