Teicos
(Teicoplanin 400 mg Injection)
Overview:
TEICOS INJECTION contains-
Teicoplanin bioavailablity when administered intramuscularly – 90%. Associated with lower incidence of nephrotoxicity or ototoxicity. Treats gram positive organism.
Teicoplanin is a type of glycopeptide antibiotic.
Bacterial infection
Osteomyelitis
Pneumonia
Cystitis
Peritonitis
Endocarditis
Osteomyelitis
Pneumonia
Cystitis
Peritonitis
Endocarditis
In serious gram +ve infections, serious staphylococcal infections in patients sensitive or unresponsive to penicillins and cephalosporins, CAPD related peritonitis, prophylaxis in orthopaedic surgery at risk of gram +ve infections.
ADULTS- 6 mg/kg as single loading dose.
CHILD-
≤2 months : 8 mg/kg via infusion once daily.
2 months to 12 years : 6-10 mg/kg once daily.
>12 years Same as adult dose.
CHILD-
≤2 months : 8 mg/kg via infusion once daily.
2 months to 12 years : 6-10 mg/kg once daily.
>12 years Same as adult dose.
Teicoplanin mediates its antibacterial activity by binding to the d-alanyl-d-alanine moiety and sequestration of the lipid II substrate, resulting in inhibition of bacterial peptidoglycan synthesis
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