Overview of Enoxaparin Sodium Injection:
LOMONOX PFS contains Enoxaparin sodium. Enoxaparin is a fractionated, low molecular weight heparin with a longer duration of action than heparin. Advantages of fractionated Low Molecular Weight Heparin over unfractionated heparin sodium:
-Once daily dosing, rather than a continuous infusion
-No need for monitoring of the APTT coagulation parameter
-Possibly a smaller risk of bleeding
-Smaller risk of heparin-induced thrombocytopenia
-Anticoagulant effects are reversible with protamine sulfate
Enoxaparin is rapidly absorbed. Its bioavailability is 90%. Metabolised by the liver, eliminated by the kidneys.
Enoxaparin sodium which is a low molecular weight heparin.
LOMONOX PFS can be used in the treatment of the following conditions:
- Deep Vein Thrombosis
- Unstable Angina & Non-Q-Wave MI
- Acute ST-segment elevation myocardial infarction (STEMI)
LOMONOX PFS 40mg once a day or LOMONOX PFS 30mg every 12 hours administered by SC injection. The usual duration of administration is 7 to 10 days. Dosage, administration and duration depends on the condition being treated, or it is as directed by Physician.
Enoxaparin Sodium is an anti-thrombotic agent that helps to prevent blood clots from forming in patients who have either undergone surgery or are suffering from a medical condition that limits their mobility. It can also treat existing blood clots in deep veins or in unstable coronary artery disease (Unstable Angina or non Q-wave Myocardial Infarction).