Nisibro D
(Dextromethorphan Hydrobromide I.P 10mg + Chlorpheniramine Maleate I.P 2mg + Phenylephrine Hydrochloride I.P 5mg)
Overview:
NISIBRO D SYRUP contains
Dextromethorphan is an agonist of NMDA (N-methyl-D-aspartate) and sigma-1 receptors, α3/β4 nicotinic receptors.
Chlorpheniramine is a histamine-H1 receptor antagonist manages symptoms associated with allergic rhinitis.
Phenylephrine is an alpha-1 adrenergic agonist mediates vasoconstriction and mydriasis .
Dextromethorphan hydrobromide is an antitussives.
Chlorpheniramine is a histamine H1 antagonist.
Phenylephrine is an alpha-1 adrenergic receptor
Rhinitis
Pharyngitis
Tonsillitis
Laryngitis
Nasal congestion
Tussis
Upper Respiratory Infection
Pharyngitis
Tonsillitis
Laryngitis
Nasal congestion
Tussis
Upper Respiratory Infection
ADULTS-
10 ml orally every 4 hours.
10 ml orally every 4 hours.
PEDIATRICS-
1.25 ml orally every 4 to 6 hours.
Chlorpheniramine binds to and activates the histamine H1 receptors. Histamine is blocked, which temporarily relieves the symptoms caused by histamine.
Phenylephrine increases peripheral vascular resistance, systolic and diastolic blood pressure. Stimulates the vagus nerve, causing reflex bradycardia.