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ARLUTE
Overview:
A fixed-dose combination of Artemether 80 mg and Lumefantrine 480 mg, offering a potent antimalarial therapy. It is effective against multidrug-resistant strains of Plasmodium and provides rapid symptom relief with minimal recurrence.
- Class
- Dosage
- Indications
- Mechanism of action
Artemisinin Combination Therapy (ACT)
Treatment of uncomplicated malaria caused by Plasmodium falciparum
Multidrug-resistant malaria
Relapse prevention after initial treatment
Artemether rapidly reduces parasite biomass by forming free radicals that damage parasite membranes, while Lumefantrine inhibits heme detoxification, starving the parasite of nutrients.