ROSIVAC
Overview:
ROSIVAC Tablets contains Rosuvastatin. Rosuvastatin is the most effective statin at reducing LDL-C, triglycerides, and total cholesterol, at the lowest dose.
- Class
- Dosage
- Indications
- Mechanism of action
Rosuvastatin is a HMG-CoA reductase inhibitor.
ROSIVAC Tablets can be used in the treatment of the following conditions:
- Hyperlipidemia and mixed dyslipidemia
- Hypertriglyceridemia
- Hypercholesterolemia
- Primary Dysbetalipoproteinemia (Type III Hyperlipoproteinemia)
- Slowing the progression of Atherosclerosis
- Primary prevention of cardiovascular diseases
Rosuvastatin that is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor for cholesterol. The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering.
Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.
