PANTONIS
Overview:
Pantonis (Pantoprazole 40 mg) is a highly effective proton pump inhibitor (PPI) used for the treatment of acid-related gastrointestinal disorders. It provides long-lasting acid suppression, promoting the healing of gastric and duodenal ulcers, GERD, and Zollinger-Ellison syndrome. Available in both tablet and injection forms, it ensures flexible treatment options for both outpatient and hospitalized patients.
- Class
- Dosage
- Indications
- Mechanism of Action
Proton Pump Inhibitor (PPI)
GERD & Erosive Esophagitis: 40 mg once daily for 4-8 weeks
Peptic Ulcer Disease: 40 mg once daily for 4-8 weeks
Zollinger-Ellison Syndrome: 40-80 mg twice daily, adjust as needed
H. pylori Eradication (Triple Therapy): 40 mg twice daily for 7-14 days (with antibiotics)
NSAID-induced Ulcer Prevention: 20-40 mg once daily
Administration: Take 30-60 minutes before a meal for best absorption.
Swallow whole; do not crush or chew.
Injection (IV) Dosage:
GERD & Peptic Ulcers: 40 mg IV once daily
Zollinger-Ellison Syndrome: 80 mg IV daily, adjust based on response
GI Bleeding Prevention: 40 mg IV every 12-24 hours
- Severe GERD (Gastroesophageal Reflux Disease)
- Peptic ulcers (gastric and duodenal ulcers)
- Erosive esophagitis
- Zollinger-Ellison syndrome (excess acid secretion)
- Stress ulcers in critically ill patients
- Gastrointestinal bleeding prevention in high-risk cases NSAID-induced ulcer prevention
- H. pylori eradication (as part of combination therapy)
Pantoprazole inhibits the proton pump (H⁺/K⁺ ATPase) in gastric parietal cells, leading to potent acid suppression. This reduces gastric acidity, alleviates acid reflux symptoms, and promotes ulcer healing.
