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TRIGNERV
Nortriptyline (10mg) and Pregabalin (75mg)
Overview:
A combination of Nortriptyline (10mg) and Pregabalin (75mg), Trignerv offers synergistic benefits for managing chronic neuropathic pain and fibromyalgia. It reduces pain perception, improves sleep quality, and enhances patient quality of life in conditions associated with nerve pain.
- Class
- Indications
- Mechanism of action
Tricyclic Antidepressant + Anticonvulsant
Neuropathic pain
Fibromyalgia
Diabetic neuropathy
Post-herpetic neuralgia
Sciatica
Anxiety-related neuropathic pain
Nortriptyline inhibits the reuptake of serotonin and norepinephrine, modulating pain perception, while Pregabalin binds to alpha-2-delta subunits of calcium channels, reducing neurotransmitter release and pain signals
