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NISKACIN
Amikacin 500mg Injection
Overview:
Amikacin is a broad-spectrum aminoglycoside antibiotic used for severe infections, especially those caused by multidrug-resistant Gram-negative bacteria. It is often used when other antibiotics fail due to resistance. Amikacin is commonly prescribed for hospital-acquired infections, particularly in critically ill patients.
- Class
- Dosage
- Indications
- Mechanism of action
Aminoglycoside antibiotic
500 mg every 12 hours (adjusted for renal function)
Amikacin 500mg Injection can be used in the treatment of the following conditions:
- Nosocomial pneumonia (ventilator-associated pneumonia)
- Septicemia (bloodstream infections)
- Urinary tract infections caused by resistant bacteria
- Bone and joint infections (osteomyelitis)
- Meningitis (bacterial)
- Intra-abdominal infections
- Multidrug-resistant tuberculosis (MDR-TB) (as part of combination therapy)
Amikacin binds to the 30S ribosomal subunit, causing errors in bacterial protein translation, leading to cell death.