CONTROMAX MK

Moxifloxacin HCI I.P eq. to Moxifloxacin 0.5% w/v + Ketorolac Tromethamine I.P. 0.5%w/v
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Overview:

A combination therapy used for preventing post-surgical infections and controlling inflammation. Moxifloxacin offers broad-spectrum antibacterial coverage, while Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps in reducing pain, swelling, and discomfort following ocular surgery.Clinical trials in the Am J Ophthalmol (2020) demonstrate superior efficacy over monotherapy in reducing inflammation by 74%.


  • Class
  • Dosage
  • Indications
  • Mechanism of action

Fluoroquinolone Antibiotic + NSAID

1 drop 3-4 times daily

Contromax MK can be used in the treatment of the following conditions:

Post-operative ocular inflammation and infection prophylaxis
Moderate-to-severe bacterial conjunctivitis with inflammatory response
Pain and photophobia associated with ocular surgery
Corneal abrasions with secondary bacterial infection

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication, while Ketorolac inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis and ocular inflammation.

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