Overview:
Loteprednol Etabonate 0.5% w/v a corticosteroid ophthalmic solution designed to manage ocular inflammation with minimal risk of increasing intraocular pressure, making it a safer option for long-term use. Research in Am J Ophthalmol (2020) demonstrated an 80% inflammation reduction with minimal IOP elevation risk.
- Class
- Dosage
- Indications
- Mechanism of action
Corticosteroid
1 drop 3-4 times daily
Lotriday can be used in the treatment of the following conditions:
Non-infectious anterior uveitis
Seasonal allergic conjunctivitis
Post-operative inflammation in ocular surgeries
Corneal graft rejection prevention
Loteprednol etabonate inhibits phospholipase A2, preventing arachidonic acid release and suppressing downstream pro-inflammatory mediators such as prostaglandins and leukotrienes, reducing ocular inflammation.
